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Over the past 300 years, population health in Europe has improved enormously, but with important differences between countries. Average life expectancy at birth has doubled, and many diseases that were once common have retreated or have become less fatal. These changes in disease patterns and their risks of death can be characterized as a series of “epidemiological transitions,” starting with the gradual suppression of “crisis mortality” in the 18th and 19th centuries and ending with the still ongoing “cardiovascular revolution” of the second half of the 20th century.